Pete Mahon's side will be looking to emulate last years' St Patrick's Week feat by taking the three points against Shamrock Rovers in Tallaght.
The Saints suffered a set back last Friday with a 3-2 defeat at home to Bray Wanderers but overcame the Wicklow men 2-0 in Monday's Leinster Senior Cup game.
Having been suspended for the first two league games, Paul Crowley again misses out with a virus. Also out is Brian Shortall who is suffering from an ankle injury but otherwise the Saints have a full squad to select from.
Saints' Assistant Manager John Gill feels that Monday's Leinster Senior Cup game may have come just at the right time.
"We were disappointed with last Friday's result and we'll be hoping to get that completely out of our system.
"Monday night's game came at a good time for us as it allowed us to get a number of players game time that will definitely stand to them.
"Some of those players will now come into contention for tomorrow's game after their performances.
"Despite the result last week we're in good shape, we have a new squad of players and we're trying to develop a new way of playing. Our training and performances have been good this year and you can see the team gelling as each week goes by.
"The atmosphere will be absolutely electric in Tallaght and these are the type of games that players dream of being involved in.
"They've had a great start to the season, beating two of the fancied teams and winning in the Setanta Cup but this is a derby game and other things come into play that make these games a bit different and a bit special.
"One bad match won't set us back and we'll be full of confidence for tomorrow's game and looking to win the game."
The Saints have only failed to score twice in their last 12 league games scoring 20 goals.
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