The Under 19s can win the SSE Airtricity League Northern Elite Division later tonight when they take on Bohemians at Dalymount Park.
Darius Kearns' side are nine points ahead of their Dublin rivals with just three game remaining and need just a point from tonight's game against second placed Bohs.
Should the Saints win their group they will enter the League Quarter Final stages and will play the fourth placed team in the Southern Elite Division.
It is just over a week since the sides met in the Final of the Enda McGuill Cup which the Gypsies won 2-1. Neill Doyle scored the opening goal for the Saints, but the visitors scored two second half goals to seal the win.